November 8, 2021

Popular artificial sweetener linked to blood clots, heart disease

The NHIRD covers nearly 99% of the population of Taiwan and is a representative data source that includes age, sex, and comorbidity information. Because each resident in Taiwan is assigned a unique personal identification number, all of the study participants could be traced through the NHI records for the entire follow-up period. This enabled us to conduct this study, which is the first nationwide study on an Asian population that contains a large sample size as well as a long follow-up period; moreover, our findings can be generalized to the entire population of Taiwan.

Is erythritol safe?

Numerous clinical observations support the notion that alcohol adversely affects the production and function of virtually all types of blood cells. Thus, alcohol is directly toxic to the bone marrow, which contains the precursors of all blood cells, as well as to the mature cells circulating in the bloodstream. Moreover, long-term excessive alcohol consumption can interfere with various physiological, biochemical, and metabolic processes involving the blood cells.

This Popular Artificial Sweetener Is Linked to Heart Attacks and Strokes, Research Shows

Cortisol is released when a person feels physical or psychological stress so that they are prepared for a threat to their well-being. Alcohol can cause an increased release of cortisol and, in does alcohol affect blood clotting turn, higher blood pressure and a faster heartbeat. Consuming alcohol leads to a lower number of blood platelets because the substance hinders the bone marrow’s ability to produce these cells.

Oxidative Stress and Apoptosis: Linked Mechanisms

Thus, the cells frequently remain at their normal locations in the tissues rather than migrate to the sites of infections. Although the different blood cells have distinct structures and functions, they are all produced at the same site, the bone marrow, in a complex process called hematopoiesis. The production of all types of blood cells begins with undifferentiated precursor cells—so-called pluripotent stem cells—that can develop into whichever cell type is needed at that time. Through a series of tightly regulated intermediary stages, these stem cells multiply, differentiate, and mature into hundreds of thousands of functional RBC’s, WBC’s, or platelets, which then can be released into the bloodstream (see figure).

Why is it a risk?

“While the FDA requires safety parameters to be established and data to be publicly accessible, this does not eliminate the need for consumers to stay informed and cautious,” he warned. It enters the bloodstream through the intestine and is primarily excreted through urine, remaining unchanged. Popular sweeteners like Truvia and certain Splenda products contain erythritol as a key ingredient. Both Splenda (Heartland Food Products Group) and Truvia declined Healthline’s request to comment on these new findings. To distinguish and analyze what you’re consuming, Richard recommends meeting with a registered dietitian nutritionist, which is often covered by health insurance, or seeking guidance from other qualified health professionals and reputable online sources.

Should You Drink Alcohol While Taking Blood Thinners?

• Generally, the outcome after severe trauma differs between men and women [28,29].
• These mechanisms contribute to the myocyte cellular changes that lead to intrinsic cell dysfunction, such as sarcoplasmic reticular dysfunction and changes in intracellular calcium handling and myocyte loss.
• Alcohol interferes with the function of the monocyte-macrophage system, with clinically significant consequences.
• And while it can occur naturally in fruits and vegetables or be made in small amounts by our own bodies, the artificial additions to foods and drinks can be significantly greater than amounts naturally found in produce.
• These data suggest that antioxidant defense mechanisms that attempt to protect the heart against oxidative damage appear to be initiated soon after drinking alcohol.

Think you have a drinking problem?

The Hematological Complications of Alcoholism